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P1306
Sigma
Peptide YY human
≥97% (HPLC), synthetic
| Synonym: | PYY, Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2 |
| CAS Number: | 118997-30-1 |
| Linear Formula: | C194H295N55O57 |
| Molecular Weight: | 4309.75 |
| MDL number: | MFCD00081843 |
Description
| Biochem/physiol Actions | Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors. |
Properties
| biological source | synthetic |
| assay | ≥97% (HPLC) |
| Gene Information | human ... PYY(5697) |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
References
| reference | Tatemoto, K., Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion. Proc. Natl. Acad. Sci. U. S. A. 79, 2514-2518, (1982) |
| Lundberg, J.M., Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility. Proc. Natl. Acad. Sci. U. S. A. 79, 4471-4475, (1982) | |
| Tatemoto, K., Isolation and primary structure of human peptide YY. Biochem. Biophys. Res. Commun. 157, 713-717, (1988) |
